Regederm 365 Retinoid Eye SerumFirming Care for Delicate Eye Area: Targets six types of fine lines around the eyes (under eye, eyelid, eye corner, eye front, tear trough, crows feet) for a smoother, more lifted look. Deep Hydration & Skin Density Boost: Improves skin moisture by 9. 8% and enhances firmness from within, reducing that tight, dry feeling around the eyes. Next Gen Retinoid (HPR) with Low Irritation: Uses Hydroxypinacolone Retinoate (HPR), a new retinoid that offers